Fig. 5
From: Effects of melatonin in polycystic ovary syndrome: is there Hippo pathway crosstalk?
Interaction between melatonin, insulin, and the Hippo pathway. Abbreviations: Gαs: stimulatory guanine triphosphate-binding protein α-subunit; cAMP: cyclic adenosine monophosphate; cAMP: cyclic guanosine monophosphate; LATS1/2: large tumor suppressor 1 and 2; YAP: Yes-associated protein; IGF-I: insulin-like growth factor; IRS-1: insulin receptor substrate-1